slanDCs in carcinoma-draining lymph nodes
نویسندگان
چکیده
Dendritic cells (DCs) are known to initiate adaptive immune responses against malignant cells. However, the role in anticancer immunosurveillance of 6-sulfo LacNAc-expressing DCs (slanDCs), a distinct population of circulating and tissue-resident pro-inflammatory DCs, is unclear. We have recently demonstrated the involvement of slanDCs in nodal immune responses against carcinoma cells.
منابع مشابه
slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells.
Dendritic cells (DCs) initiate adaptive immune responses to cancer cells by activating naive T lymphocytes. 6-sulfo LacNAc(+) DCs (slanDCs) represent a distinct population of circulating and tissue proinflammatory DCs, whose role in cancer immune surveillance is unknown. Herein, by screening a large set of clinical samples, we demonstrate accumulation of slanDCs in metastatic tumour-draining ly...
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2014